Getting the message: BRCA1/2 transcript levels in ovarian cancer

Tony Fischer, formerly of Iowa Interdisciplinary Genetics fame, will be one of two students presenting for MSTP (click link to see Abe’s mug on the homepage) Grand Rounds this Friday regarding the involvement of BRCA1/2 gene transcription in ovarian cancer.  Given the importance of these genes in breast cancer, the involvement of these two genes has not been as closely examined in ovarian cancer although they play a substantial role.  The talk will be in 2117 MERF @ 12:30 on Friday, October 17th.  Refreshments (free food) @ 12:15.  The link for the poster is here.  Tony always gives great presentations and should be interesting to see him in action again.

10.28.08 update…One of the interesting findings presented was that a miRNA (miR 146) is capable of targeting both the BRCA1 and BRCA2 transcipts.

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Posted on October 14, 2008, in Other and tagged , , , , , . Bookmark the permalink. 1 Comment.

  1. Tony did a great job presenting a clinical ovarian cancer case while Ginny Harris presented some of the current research related to BRCA1 and BRCA2. One of the interesting findings was that a miRNA could target both BRCA1 and BRCA2 (specifically the 3′ UTR, I believe) making it a very interesting candidate for breast/ovarian cancer. I believe this may be the paper that Ginny pulled some of this info from: http://carcin.oxfordjournals.org/cgi/content/full/29/10/1963.

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